Nothing is undruggable
Talus Bioscience is unlocking transcription factor therapeutics for cancer and beyond.
Our highly interdisciplinary team are pioneers in proteomics-first drug discovery for transcription factors, with more than 6,800 citations, 50% PhD scientists, and two “40-under-40” proteomicists.


We have built the first platform to target transcription factors in their native cellular environments
We bring together functional proteomics, automated biology, and machine learning to discover drugs for challenging targets in live human cells. To start, we are finding new treatments for rare, incurable childhood cancers driven by genome regulators.
Leadership Team
Talus Bio team members cover a wide spectrum of scientific expertise and experience with backgrounds in medicinal chemistry, molecular biology, cancer research, mass spectrometry, computational science, and machine learning. With diverse experience and perspectives, our team is uniquely positioned to collectively explore all angles of the transcription factor therapeutics problem, accelerating breakthroughs and developing solutions faster.
Our team members cover a wide spectrum of scientific expertise and experience with backgrounds in medicinal chemistry, molecular biology, cancer research, mass spectrometry, computational science, and machine learning.
With diverse experience and perspectives, our team is uniquely positioned to collectively explore all angles of the transcription factor therapeutics problem, accelerating breakthroughs and developing solutions faster.
Our Technology
We have built a platform that enables drug discovery and development for previously undruggable genome regulators.
Drug Pipeline
Innovations in automated cell processing, next-gen proteomics, and advanced data analytics to measure a drug's effect on the entire regulome.
Join Our Team
We’re committed to building a diverse, inclusive, and empowering workplace of team members excited to serve healthcare communities around the world.