Nothing is undruggable
By bringing together innovators in emerging technologies, Talus Bio is unlocking transcription factor therapeutics for cancer.
We are building first-in-class drugs that target previously undruggable transcription factors. Our platform uses automated biology, next-gen proteomics, synthetic chemistry, and computation to engineer and interrogate drugs, proteins, and genomics at an unprecedented scale.


We have built the first platform to target transcription factors in their native cellular environments
We bring together functional proteomics, automated biology, and machine learning to discover drugs for challenging targets in live human cells. To start, we are finding new treatments for rare, incurable childhood cancers driven by genome regulators.
Our Technology
We have built a platform that enables drug discovery and development for previously undruggable genome regulators.
Drug Pipeline
Innovations in automated cell processing, next-gen proteomics, and advanced data analytics to measure a drug's effect on the entire regulome.
Our Team
Our team are pioneers in proteomics-first drug discovery for transcription factors, with >6,800 citations, 50% PhD scientists, and two "40-under-40" proteomicists